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Lexicon: L
Legionella and frequency therapy
Definition:
Legionella is a genus of rod-shaped bacteria that are found in natural water sources and can thrive in artificial water systems under certain conditions. They are known to cause Legionnaires' disease, a severe form of pneumonia, as well as the milder Pontiac fever.
species:
The best known and most commonly associated with disease outbreaks is *Legionella pneumophila*. However, there are over 60 other species, some of which can also be pathogenic.
Transmission:
- Legionella spreads mainly through inhalation of aerosols containing the bacteria, which can occur in showers, air conditioning systems, whirlpools and cooling towers.
- Direct transmission from person to person is not known.
Diseases:
- Legionnaires' disease: A severe pneumonia that causes fever, coughing, shortness of breath, muscle pain and headaches. It can be particularly severe in older people, smokers and people with a weakened immune system.
- Pontiac fever: A flu-like illness without pneumonia that is milder and characterised by fever, headaches and muscle aches.
Diagnosis:
- Cultural cultivation: Detection of Legionella in respiratory secretions or tissue samples.
- Antigen tests: Detection of Legionella antigens in urine.
- PCR tests: Molecular methods for the detection of Legionella DNA.
Treatment:
- Legionnaires' disease is treated with antibiotics, with macrolides (such as azithromycin) or fluoroquinolones (such as levofloxacin) commonly used.
- Pontiac fever is self-limiting and usually requires no specific treatment.
Prevention:
- Regular maintenance and disinfection of water systems to prevent the growth of Legionella.
- Monitoring water temperatures, as Legionella multiplies best at temperatures between 20 and 50 degrees centigrade.
- use of filtration systems and chemical treatments in water systems that are susceptible to contamination.
Worth knowing:
- Legionnaires' disease was first described in 1976 after an outbreak at a veterans' reunion in Philadelphia, which led to the discovery of *Legionella pneumophila*.
- Legionella is widespread in the environment, but only leads to outbreaks under certain conditions.
Research:
Research is focussed on improving diagnostic methods, developing more effective prevention strategies and understanding the mechanisms by which Legionella causes disease.