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Lexicon: L
Leptospirosis and frequency therapy
definition:
Leptospirosis is a bacterial infectious disease caused by spiral bacteria of the genus *Leptospira*. It can affect both humans and animals and is often transmitted through contact with contaminated water or soil.
Pathogen:
The disease is caused by different serovars of *Leptospira* that can survive in moist environments. The bacteria are able to enter the body through the skin or mucous membranes.
Transmission:
- Direct contact with urine of infected animals, especially rodents, dogs, pigs and cattle.
- Contact with contaminated water, soil or food.
- The bacteria can enter the body through skin lesions or mucous membranes (eyes, nose, mouth).
Symptoms:
The symptoms of leptospirosis can vary and range from mild to severe: - fever, headache, muscle pain
- Reddening of the eyes, skin rashes
- Nausea, vomiting, diarrhoea
- In severe cases, organ failure, meningitis or Weil's disease can occur, which is characterised by jaundice, kidney failure and bleeding.
Diagnosis:
- Serological tests: Detection of antibodies against *Leptospira*.
- PCR tests: Molecular methods for the detection of *Leptospira* DNA.
- Culture cultivation: Isolation of the bacteria from blood, urine or tissue samples.
Treatment:
- Antibiotics: Penicillin or doxycycline are the most common treatment options, especially in the early stages of the disease.
- Supportive therapy: treatment of complications such as kidney failure or meningitis in severe cases.
Prevention:
- Avoiding contact with potentially contaminated water or soil, especially in endemic areas.
- Protective clothing and equipment when working in humid environments.
- Vaccination of pets and livestock in risk areas.
Worth knowing:
- Leptospirosis is widespread worldwide, but is more common in tropical and subtropical regions, especially after heavy rainfall or flooding.
- The disease is a recognised occupational disease among farmers, veterinarians and other people who have close contact with animals or contaminated water.
Research:
Research is focussed on developing more effective vaccines, improving diagnostic methods and understanding the pathogenesis and epidemiology of leptospirosis.