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Lexicon: L
Leukoplakia and frequency therapy
Definition:
Leukoplakia is a condition characterised by the appearance of white, non-wipeable patches or plaques on the mucous membranes, particularly in the mouth. These lesions are potentially precancerous, which means that in some cases they can develop into cancer.
Causes:
The exact cause of leukoplakia is not fully understood, but several factors may increase the risk:
- Tobacco use: smoking and chewing tobacco are the most common risk factors.
- Alcohol consumption: Excessive alcohol consumption can increase the risk.
- Chronic irritation: Ill-fitting dentures, sharp teeth or other mechanical irritants.
- Human papillomavirus (HPV): Some studies have shown a link between HPV and leukoplakia.
Symptoms:
- White or grey patches in the mouth that cannot be wiped off.
- The patches may be flat or slightly raised and have a rough or leathery texture.
- Usually painless, but may be sensitive to touch or spicy foods.
Diagnosis:
- Clinical examination: Visual inspection of the oral cavity by a dentist or doctor.
- Biopsy: Removal of a tissue sample for histological examination to rule out dysplasia or cancer.
Treatment:
- Elimination of risk factors:
Cessation of tobacco and alcohol consumption, adjustment of dentures or treatment of mechanical irritation. - Monitoring:
Regular check-ups to observe changes in the lesions. - Surgical removal:
In some cases, removal of the lesions may be necessary, especially if dysplasia is detected.
Prevention:
- Avoidance of tobacco and excessive alcohol consumption.
- Regular dental examinations for early detection of changes in the oral mucosa.
- Good oral hygiene and care of dentures.
Worth knowing:
- Not all white patches in the mouth are leukoplakia; other conditions such as oral candidiasis (oral thrush) can cause similar symptoms.
- Although many cases of leukoplakia remain benign, regular monitoring is important to ensure early detection and treatment of potential malignant changes.
Research:
Research is focused on understanding the molecular mechanisms that lead to the development of leukoplakia and developing strategies for prevention and treatment to minimise the risk of malignant transformation.