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Multiple sclerosis and frequency therapy
**Encyclopaedia entry: Multiple sclerosis (MS)**
**Definition:**
Multiple sclerosis (MS) is a chronic, inflammatory disease of the central nervous system that affects the brain and spinal cord. It causes damage to the myelin sheaths surrounding nerve fibres, which disrupts communication between nerve cells.
**Causes:**
The exact cause of MS is unknown, but a combination of genetic, immunological and environmental factors is thought to play a role. MS is thought to be an autoimmune disease in which the immune system mistakenly attacks myelin.
**Symptoms:**
Symptoms of MS can vary greatly and depend on which nerves are affected. Common symptoms are:
- Visual disturbances, such as blurred vision or double vision
- Muscle weakness and coordination problems
- Numbness or tingling in the limbs
- Tiredness and fatigue
- Balance problems and dizziness
- Bladder and bowel problems
- Cognitive impairments, such as memory problems
**Progression:**
MS often progresses in relapses, alternating with periods of remission. There are different forms of progression:
- **Remitting relapsing-remitting MS (RRMS):** Most common form, characterised by clear relapses and remissions.
- **Secondary progressive MS (SPMS):** Develops from RRMS and leads to a steady worsening of symptoms.
- **Primary progressive MS (PPMS):** Rarer form in which symptoms progress continuously from the beginning.
**Diagnosis:**
The diagnosis of MS is based on a combination of:
- **Clinical examination:** Assessment of neurological symptoms.
- **Magnetic resonance imaging (MRI):** To detect lesions in the brain and spinal cord.
- **Lumbar puncture:** Examination of cerebrospinal fluid for inflammatory markers.
- **Evoked potentials:** Tests to measure nerve responses to stimuli.
**Treatment:**
There is no cure for MS, but treatment aims to relieve symptoms, shorten relapses and slow the progression of the disease:
- **Immunomodulatory therapies:** Drugs such as interferons and glatiramer acetate to reduce the frequency of relapses.
- **Corticosteroids:** For the treatment of acute relapses.
- **Symptomatic treatments:** Physiotherapy, painkillers and medication to treat specific symptoms such as spasticity or bladder problems.
**Prevention and management:**
- Regular medical care and adaptation of therapy.
- Healthy lifestyle with a balanced diet and regular exercise.
- Stress management and sufficient sleep to prevent relapses Stress management and adequate sleep to support wellbeing.
**Lessons to know:**
- MS affects millions of people worldwide and is more common in women than men.
- The disease is usually diagnosed in young adulthood, between the ages of 20 and 40.
**Research:**
Research into MS focuses on understanding the mechanisms of the disease, developing new therapies and improving the quality of life of those affected.