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Lexicon: N
NovoTTF-100A device
The NovoTTF-100A device is an innovative medical device used for the treatment of recurrent glioblastoma. It uses alternating electric fields that are applied to the skin over the tumour-bearing areas of the body.
How it works:
- Alternating electric fieldsthese fields are generated by electrodes that are placed on the skin. The fields interfere with cell division and inhibit the growth of tumour cells.
- Frequency rangethe device operates in the frequency range from 200 kHz to 300 kHz.
Clinical data:
- Phase III studyin a randomised phase III trial, the NovoTTF-100A device showed efficacy comparable to standard chemotherapy, but with fewer side effects.
- FDA approvalbased on the results of this study, the device was the first of its kind to be approved by the FDA in the USA.
Advantages:
- Non-invasivethe treatment is non-invasive and can be performed at home.
- Fewer side effectscompared to standard chemotherapy, there are fewer side effects.
Application:
- Glioblastomathe device is mainly used for the treatment of recurrent glioblastoma, an aggressive form of brain tumour.
The NovoTTF-100A device offers a promising alternative treatment method for patients with recurrent glioblastoma that is less burdensome and yet effective against tumour cells.