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Lexicon: S
Shaking palsy and frequency therapy
**Lexicon entry: Shaking palsy**
**Definition:**
Shaking palsy is an outdated term that was historically used to describe the neurological disorder Parkinson's disease. Parkinson's disease is a chronic, progressive movement disorder caused by the loss of dopamine-producing nerve cells in the brain.
**Causes:**
The exact cause of Parkinson's disease is unknown, but a combination of genetic and environmental factors are thought to play a role. The loss of dopamine in the brain leads to the characteristic movement disorders.
**Symptoms:**
The symptoms of Parkinson's disease develop gradually and can vary, but often include:
- **Tremor:** Trembling, usually at rest, often starting in one hand.
- **Bradykinesia:** Slowing of movement, making everyday activities difficult.
- **Rigor:** Muscle stiffness that restricts movement and can cause pain.
- **Postural instability:** Balance problems that can lead to falls.
- **Other symptoms:** Speech changes, reduced facial expression, sleep disturbances and cognitive impairment.
**Diagnosis:**
The diagnosis of Parkinson's disease is based on medical history, clinical examination and exclusion of other diseases. There is no specific test for diagnosis, but imaging techniques such as MRI or DaTSCAN can be used to assist.
**Treatment:**
There is no cure for Parkinson's disease, but treatment aims to alleviate symptoms and improve quality of life:
- **Medication:** Levodopa is the most effective medication for increasing dopamine levels in the brain. Other medications such as dopamine agonists and MAO-B inhibitors can also be used.
- **Physiotherapy:** To improve mobility and balance.
- **Ergotherapy:** Support in coping with everyday life.
- **Surgical interventions:** Deep brain stimulation (DBS) may be considered in advanced cases.
**Prevention and management:**
- Regular medical care and adaptation of therapy.
- Healthy lifestyle with a balanced diet and regular exercise.
- Support from self-help groups and specialised medical centres Support from self-help groups and specialised carers.
**Fun facts:**
- Parkinson's disease is named after the British physician James Parkinson, who first described the disease in 1817.
- It affects millions of people worldwide and is more common in older adults.
**Research:**
Research into Parkinson's disease focuses on understanding the mechanisms of the disease, developing new drugs and therapies and improving diagnosis and treatment methods.